http://hdl.handle.net/20.500.14044/37467 2026-07-26T00:43:50Z 2026-07-26T00:43:50Z Kóra, Szilvia Prontvai, Nándor Törő, Blanka Kós, Petra Drótár, István Prukner, Péter Wersényi, György Haidegger, Tamás Tollár, József http://hdl.handle.net/20.500.14044/38754 2026-06-18T05:21:19Z 2023-01-01T00:00:00Z

Virtual Reality in Cerebrovascular Rehabilitation: A Mini Review on Clinical Efficacy and Neurological Impacts Kóra, Szilvia; Prontvai, Nándor; Törő, Blanka; Kós, Petra; Drótár, István; Prukner, Péter; Wersényi, György; Haidegger, Tamás; Tollár, József The application of virtual reality (VR) technology in both upper and lower limb rehabilitation represents a significant advancement in the field of medicine. VR-based therapies provide patients with the opportunity to engage in intensive, repetitive, and targeted exercises that promote neuroplasticity and improve the motor skills necessary for daily life. VR has long been recommended for the rehabilitation of conditions such as in case of ischemic stroke, Parkinson’s disease, and multiple sclerosis, further underscoring its versatility and therapeutic potential. In our study, we evaluated the effectiveness of VR therapy focusing on stroke rehabilitation. The reviewed VR systems provided motion analysis, tracking, feedback reinforcement, and realistic environments to facilitate the restoration of motor functions. Furthermore, we developed a VR-based therapy aimed at both upper and lower limb motor functions, combined with traditional rehabilitation. The application of VR technology not only promotes the improvement of motor functions but also offers economic advantages by reducing the burden on healthcare workers and increasing rehabilitation capacity. Further research is needed to determine the optimal conditions for applying VR therapy in clinical practice.

2023-01-01T00:00:00Z Kóra, Szilvia Prontvai, Nándor Törő, Blanka Kós, Petra Drótár, István Prukner, Péter Wersényi, György Haidegger, Tamás Tollár, József http://hdl.handle.net/20.500.14044/38752 2026-06-18T05:20:44Z 2023-01-01T00:00:00Z

Telerehabilitation After Brain Injuries: Its Efficacy and Role in Reducing Healthcare Burdens Kóra, Szilvia; Prontvai, Nándor; Törő, Blanka; Kós, Petra; Drótár, István; Prukner, Péter; Wersényi, György; Haidegger, Tamás; Tollár, József Rehabilitation following brain injuries, such as stroke and other traumatic injuries, presents significant challenges for both patients and healthcare systems. Traditional in- person rehabilitation often requires regular visits to specialized facilities, which can be difficult for patients in remote areas or those with mobility and financial constraints. Telerehabilitation offers a promising solution by enabling patients to continue essential therapy at home, ensuring continuity of care while reducing the burden on healthcare providers. It can be effectively applied across various patient groups, including children, adults, the elderly, amputees, individuals with traumatic neurological injuries, and those with neurocognitive impairments such as dementia. Our telemedicine platform integrates advanced technologies, i.e., 3D motion analysis and Virtual Reality (VR) to enhance home- based physiotherapy. These tools enable precise monitoring, real-time feedback, and immersive therapy sessions, in order to improve coordination, fine motor skills, hand-eye coordination, and the vestibular system, which is crucial for balance. This platform also performs detailed offline data analysis, allowing healthcare professionals to adjust therapy plans based on individual needs. As the demand for rehabilitation services continues to grow, adopting these technologies will be crucial for sustainable, effective healthcare, ultimately improving patient outcomes and shaping a more efficient and equitable future for healthcare systems.

2023-01-01T00:00:00Z Péntek, Márta Zrubka, Zsombor Gulácsi, László Weszl, Miklós Czere, János Tibor Haidegger, Tamás http://hdl.handle.net/20.500.14044/38751 2026-06-18T05:21:25Z 2023-01-01T00:00:00Z

10 Pragmatic Points to Consider When Performing a Systematic Literature Review of Clinical Evidence on Digital Medical Devices Péntek, Márta; Zrubka, Zsombor; Gulácsi, László; Weszl, Miklós; Czere, János Tibor; Haidegger, Tamás Innovative Digital Medical Devices (DMDs) are gaining a growing importance in healthcare, thus the interest regarding their actual clinical value is increasing. Gathering and evaluating all available clinical evidence on a device is needed for the developers, manufacturers, notified bodies (certification), product managers, clinicians and, above all, for the users. Systematic Literature Review (SLR), is a scientific, standardized method, often used to identify and evaluate all available evidence on a relevant question, hence this method is widely used and accepted to provide high-quality evaluations on clinical evidence. Moreover, the Medical Device Regulation (EU 2017/745) also considers clinical evidence derived from the peer-reviewed scientific literature for the assessment of medical devices being adequate, considering even sustainability aspects. Researchers therefore can actually contribute to the clinical assessment of novel DMDs through the rigorous assessment of the State-of-the-art and the comprehension of the existing levels of evidence. Although the methodology of SLRs has been established in the past decades, some specific questions arise when it comes to DMDs. The objective of this paper was, therefore, to establish a set of practical points to consider in SLRs of clinical evidence on DMDs. We believe that our work helps to speed up DMD development, authorization, management and implementation, thereby eventually, contribute to the health of patients.

2023-01-01T00:00:00Z Kucarov, Marianna Dimitrova Molnár, Béla Kozlovszky, Miklos http://hdl.handle.net/20.500.14044/38749 2026-06-18T05:22:37Z 2023-01-01T00:00:00Z

Localization and Conversion of Single Cell Positions from Static High-Resolution Digital Images to Lasermicrodissector Coordinate System through Utilization of References and 2D Transformation Techniques Kucarov, Marianna Dimitrova; Molnár, Béla; Kozlovszky, Miklos laser microdissection technique for tissue excision has been developed to replace the slow, manual positioning of the laser with a roller. The method consists of the 3DHistech- P1000 digital tissue scanner, MorphCheck evaluation software, and integration of the MMI CellCut laser microdissector. To create a seamless integration between the workflows, a digital reference selection; rotational, translational, and conversion transformation of Region of Interest (ROI) coordinates from pixel-based images to the mm-based coordinate system of the laser unit; a fused database loaded with parameters (image, shape, position, unique identifier) of the analyzed slides and the selected ROIs, and XML-based communication have been developed. The software implementation has been tested on the microdissector device. The application of the method results in an automated workflow that allows laser excision with an accuracy of 2 μm and a standard deviation of 2.2 μm, which requires the selection of at least three cell clusters of ROIs to perform laser excision without live image based on a predefined static image.

2023-01-01T00:00:00Z